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10.1007/s11357-024-01176-2 Geroscience 136 MinokoshiY.AlquierT.FurukawaN.KimY

In this context, glutathione S-transferases (GSTs) finds an important mention as members of this family quench reactive molecules and catalyze the conjugation of GSH to an array of hydrophobic and electrophilic substrates, thus, protecting the cell from oxidative burst

Studies have shown that oxidative stress and inflammation can negatively impact brain health

The pentahydroxy flavone protect from oxidative injury and cell death by scavenging free radicals, donating hydrogen compound, quenching singlet oxygen, and shielding lipid peroxidation or chelating metal ions [160]